Mahāsutasomajātaka

Suttapiṭaka · Khuddakanikāya · Jātaka (2) · Vol. 28 · Section 377

[377] Whoever indeed, thinking, "This is dear to me," keeps guard over things dear, and, casting himself aside, indulges in things dear — like a drunkard who has drunk a bowl mixed with poison — for that very reason he comes to suffering (dukkha) in the world hereafter. But whoever here, having considered, abandons things dear, and pursues the noble dhammas (ariyadhamma), even with hardship — like a man afflicted who has drunk his medicines — for that very reason he comes to happiness in the world hereafter.

English translation from the Pali (Siam Raṭṭha edition) — under review, not for citation.